Valganciclovir hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

缬更昔洛韦（盐酸盐）是更昔洛韦的L-缬氨酰酯，实际上是更昔洛韦的前药。

Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.

Cell Viability Assay Cell Line:A549 cells Concentration:500 μM Incubation Time:5 days, 7days Result:Showed EC50 values ranged from 120.5 μM (Ad4) to 244.4 μM (Ad6).Showed IC50 values was calculated to be 11.74 mM at 7 days post-infection.

Animal Model:Immunosuppressed hamstersDosage:200 mg/kg Administration:Oral gavage (p.o.)Result:Resulted in significantly smaller magnitude of weight loss for all groups.Reduced the liver pathology.

Ro 107-9070/194 | Valcyte

Others

Other Targets

CMV

Infection

——

175865-59-5

390.82

C14H23ClN6O5

>98% (HPLC)

Water: 78 mg/mL (199.58 mM); DMSO: 78 mg/mL (199.58 mM)

CC(C)[C@H](N)C(OCC(OCN1C=NC2=C1NC(N)=NC2=O)CO)=O.[H]Cl

[2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] (2S)-2-amino-3-methylbutanoate hydrochloride

(-20℃)

With Ice Pack

≥ 2 years